Month: December 2024

FDA approves first medication for obstructive sleep apnea, promotes weight loss

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The first medication for obstructive sleep apnea has been approved by the U.S. Food and Drug Administration (FDA).

On Dec. 20, the FDA announced that the agency has approved Eli Lilly’s Zepbound (tirzepatide) to treat moderate to severe obstructive sleep apnea (OSA) in adults with obesity.

The drug is to be paired with a reduced-calorie diet and increased physical activity, the FDA noted.

SOME SLEEP APNEA PATIENTS SEE IMPROVEMENT WITH NEW BREATHING TOOL

Sally Seymour, M.D., director of the Division of Pulmonology, Allergy and Critical Care in the FDA’s Center for Drug Evaluation and Research in Washington, D.C., applauded the approval in an announcement.

Happy and healthy senior man sleeping deeply on his left side without snoring (iStock)

“Today’s approval marks the first drug treatment option for certain patients with obstructive sleep apnea,” Seymour wrote. “This is a major step forward for patients with obstructive sleep apnea.”

OSA occurs when the upper airway becomes blocked and causes pauses in breathing during sleep, according to the FDA. The condition is more common in people who are overweight or obese.

UNTREATED SLEEP APNEA PRESENTS ‘DISRUPTIVE’ DANGERS TO PEOPLE’S LIVES, INCLUDING HEART ISSUES, SAYS EXPERT

Similar to semaglutide treatments like Ozempic and Wegovy, Zepbound activates receptors of hormones secreted from the intestine (GLP-1 and GIP) to reduce appetite and food intake.

About 30 million people suffer from sleep apnea in the U.S.

Studies show that by reducing body weight, Zepbound “also improves OSA,” the FDA noted.

In a 52-week study, participants treated with Zepbound experienced “statistically significant and clinically meaningful reduction in events of apnea or hypopnea,” and a large share of participants achieved remission or “resolution of symptoms.”

man with obesity sleeps

Zepbound improves obstructive sleep apnea by reducing body weight, studies show. (iStock)

Zepbound-treated patients also reported a significant decrease in body weight, the FDA mentioned.

The drug can reportedly cause side effects like nausea, diarrhea, vomiting, constipation, stomach discomfort and pain, injection site reactions, fatigue, allergic reactions (typically fever and rash), burping, hair loss and gastroesophageal reflux disease.

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While Zepbound causes thyroid C-cell tumors in rats, it’s unknown whether it causes these tumors in humans, so it should not be used by patients with a personal or family history of medullary thyroid cancer or with multiple endocrine neoplasia syndrome type 2, per the FDA.

The agency encourages all OSA patients to consult with a doctor before taking Zepbound and to monitor for any complications.

man and woman sleeping in a bedroom

One sleep expert called the FDA’s approval a “promising advancement for the millions of people who suffer from this condition.” (iStock)

Sleep expert Dr. Wendy Troxel, who is a RAND Corporation senior behavioral specialist and licensed clinical psychologist in Utah, called the FDA’s approval a “promising advancement for the millions of people who suffer from this condition.”

“Zepbound promotes weight loss and has been shown to reduce apnea events.”

About 30 million people suffer from sleep apnea in the U.S., Troxel told Fox News Digital.

While the most common treatment for sleep apnea — positive airway pressure (PAP) — is “highly effective” at treating the condition, up to 50% of patients are “non-adherent,” she said.

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“Zepbound promotes weight loss and has been shown to reduce apnea events,” Troxel noted.

“For obese individuals with moderate to severe sleep apnea, this new treatment option may offer an important alternative or adjunctive treatment, particularly for those who struggle with sleep apnea therapies, such as positive airway pressure.”

man snoring while sleeping

People with a history of severe allergic reaction to tirzepatide should not use Zepbound, the FDA warned in a news release. (iStock)

Troxel added that treating sleep apnea is “critical not only for the patient’s health and well-being, but also for their bed partners, who are often the ‘hidden casualties’ of untreated sleep apnea, given that loud snoring and gasping for air are primary symptoms,” she said.

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Dr. William Lu, medical director of Dreem Health in San Francisco, told Fox News Digital that obesity and sleep apnea are “two of the most prevalent health conditions that affect Americans today.”

“We still need to emphasize shifting the diet and health habits of many, but this is a fantastic start.”

“And they go hand in hand,” he said. “For the patients who qualify and have no contraindications, tirzepatide has the opportunity to be a generational medication that can help people lose weight, reduce the severity of sleep apnea and improve overall health.”

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“We still need to emphasize shifting the diet and health habits of many, but this is a fantastic start.”

Getting tested for sleep apnea is “critical for your health,” Lu said, and could also be a requirement for getting coverage for the medication. 

Fox News Digital reached out to Eli Lilly requesting comment.

Watch: UK Woman Eats Huge Pile Of Cotton Candy In One Minute, Sets New Record

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Leah Shutkever from the UK has set a new Guinness World Record for eating the “most cotton candy (candy floss) in one minute,” devouring 49 grams (1.72 oz) in 60 seconds. Known for holding multiple food record titles, Shutkever achieved this latest feat just in time for Christmas. The Guinness World Records shared a video of her attempt on Instagram. Staying festive, Shutkever chose green candy floss, representing the Grinch. Candy floss, a sugary treat made by heating and spinning sugar, is often associated with fairs and carnivals. After completing the challenge, Shutkever described the experience as “absolutely delicious.”
“Merry cotton candy Grinchmas to one and all,” Guinness World Records commented on the video.

Also Read:Blindfolded Man Cuts Cucumbers With A Chainsaw To Set Guinness World Record

The speed eating record garnered a range of reactions in the comments section:

“I feel like I could beat that record easily,” an Instagram user wrote. Another added, “I could do that in 20 seconds.”

Also Read: Man Breaks 2 Records For Drinking One Litre Of Acidic Lemon And Lime Juice Each In Seconds

Enjoying this challenge, a viewer said, “Grinch Candy Floss 10/10.” One suggested, “You can just roll the Cotten candy into a ball and eat that in 5 seconds.”

“Oh the hot dog girl,” a user commented, remembering Shutkever’s 2021 record for the fastest time to eat a hot dog with no hands. The “serial speed eater” achieved the feat in just 18.15 seconds. Watch the video here.

Xi presents order to promote military officer to rank of general

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<img src='https://news.cgtn.com/news/2024-12-23/Xi-presents-order-to-promote-military-officer-to-rank-of-general-1zzpyhhcwhi/img/e5a1093c430648378a0adee24d5c5661/e5a1093c430648378a0adee24d5c5661.png' alt='Xi Jinping, chairman of the Central Military Commission (CMC), presents a certificate of order to promote Chen Hui, Political Commissar of the Army of the People's Liberation Army, to the rank of general, at a ceremony in Beijing, China, December 23, 2024. /CMG'

Xi Jinping, chairman of the Central Military Commission (CMC), on Monday presented a certificate of order to promote a military officer to the rank of general.

The promoted officer is the Political Commissar of the Army of the People’s Liberation Army (PLA) Chen Hui.

Zhang Youxia, vice chairman of the CMC, announced the order of promotion, which was signed by Xi, at a ceremony held for the promotion in Beijing. He Weidong, another CMC vice chairman, presided over the ceremony.

Xi extended his congratulations to the general.

Oberoi Realty to set up hotel, villas on 81-acre land parcel in Alibag

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Oberoi Realty said it has executed an agreement for the development of an 81-acre parcel of land situated at village Tekali, Alibag in Maharashtra where it plans to develop a hotel or a resort and residential villas.

The Mumbai-based real estate developer said that on around 8.6 acres or 34,803 square meters of the land it intended to construct a high-end luxury five-star hotel or a resort with a floor space index of 30,000 square metres.

On the balance land of 72.45 acres the company intends to construct about 150 high end luxury, fully serviced, branded residential villas with FSI of around 1.2 lakh square metres.

The company said it has taken physical possession of the land, and the landowners will be compensated in the firms of revenue and area share in the residential project.

  • Also read: Broker’s call: Oberoi Realty (Buy)

Evo kako rade trgovine na Badnjak, Božić i Svetog Stjepana

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